Polycystic Kidney Disease
Polycystic Kidney Disease (PKD)
PKD is a genetic disorder that causes numerous cysts to form on the kidneys. These cysts can grow over time and eventually damage the kidneys, leading to kidney failure. PKD is the fourth leading cause of kidney failure in the United States.
Causes of PKD
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​PKD is a genetic disorder caused by mutations in the PKD1 or PKD2 genes. These mutations cause the formation of cysts on the kidneys. PKD can be inherited in an autosomal dominant manner, which means that a person only needs to inherit one copy of the mutated gene from either parent to develop the condition.
Symptoms of PKD​
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The symptoms of PKD may include:
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Pain or discomfort in the abdomen or back
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Blood in the urine
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Frequent urination
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High blood pressure
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Kidney stones
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Urinary tract infections
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Fatigue
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Headaches
Diagnosis of PKD
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PKD is typically diagnosed using imaging tests such as ultrasound, CT scans, or MRI. These tests can detect the presence of cysts on the kidneys. Genetic testing can also be performed to confirm the diagnosis.
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Treatment of PKD
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There is currently no cure for PKD. Treatment options may include:
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Managing high blood pressure with medications
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Treating urinary tract infections with antibiotics
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Pain management with medications or surgery
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Dialysis, a procedure that filters blood artificially
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Kidney transplantation, a surgical procedure that replaces a diseased kidney with a healthy one from a donor
Conclusion:​
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PKD is a genetic disorder that causes cysts to form on the kidneys, leading to kidney damage and eventual kidney failure. If you have a family history of PKD or are experiencing any symptoms of the condition, it is important to consult with your doctor for diagnosis and treatment. Managing high blood pressure, treating infections, and kidney transplantation are some of the treatment options available for PKD.
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